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Robotic surgery has witnessed explosive growth. Currently (2018) more than 3 million procedures have been performed using the da Vinci system worldwide.
Robotic surgery is not true autonomous surgery but instead the robot is used as mechanical “helping hands” aiding skilled surgeons.
By creating three-dimensional views, allowing increased movement of laparoscopic instruments within a patient’s body, and allowing precise movements, robotic surgery can enhance a surgeon’s ability to visualize pathologies and to perform complex procedures.
Given the size of robotic equipment and the need for specific patient position during procedures, robotic surgery may present unique challenges for anesthesia providers.
To facilitate surgical exposure, robotic surgery often requires insufflation of a body cavity with carbon dioxide. Insufflation and resorption of carbon dioxide can lead to a variety of physiologic changes.
Robotic surgery has been successfully used to care for patients receiving urologic, gynecologic, colorectal, hepatobiliary, otolaryngologic, cardiac, and thoracic procedures.
The authors would like to acknowledge Sumeet Goswami, Priya Kumar, and Berend Mets for contributions they made in prior versions of this chapter.
According to Merriam-Webster, a robot is “a machine that resembles a living creature in being capable of moving independently (as by walking or rolling on wheels) and performing complex actions (such as grasping and moving objects).” Developed in the 1980s by the National Aeronautics and Space Administration (NASA), a robot is a remotely controlled device that allows tasks to be performed in spaces removed from human presence. Eventually, robots began to perform tasks aboard NASA spaceships. While the initial concept of robotic science was useful in space exploration, the U.S. government began looking for other applications of the technology.
The US Department of Defense (DOD) began working to apply the robots that were useful in space to the battlefield. Recognizing that an inordinate number of American soldiers died on the battlefield from hemorrhage or untreated surgical wounds, the DOD looked to use these technologies in surgical theaters. With the goal of having a surgeon remotely operate on patients in difficult-to-reach locations, the military invested in developing remotely controlled articulating arms that could perform surgical procedures.
At the same time, the world’s first laparoscopic cholecystectomy was performed in France. This procedure forever altered the course of traditional surgery, and the minimally invasive era of surgical procedures began.
Over the next decade, several companies developed a variety of medical robots and rapidly advanced the science. The first such device appeared in the early 1990s, when an instrument was created to pulverize bone and create space for hip prosthesis during orthopedic surgery.
As work progressed on creating devices to perform procedures, work also continued on allowing remote control of devices. In the mid-1990s, voice recognition software was used to control a laparoscope’s position and to aid in organ retraction during traditional laparoscopic surgery. This device, called Automated Endoscopic System for Optimal Positioning (AESOP), is still available today ( Fig. 71.1 ). In many ways, this device was the precursor to the smart devices in our homes and on our persons.
Arguably the greatest advancement in robotic surgery occurred in 1991 when a master-slave version of a robot was developed. This device allowed a surgeon to sit apart from his/her patient and remotely control articulating arms. Two similar devices, the da Vinci Robotic Surgical System, and the ZEUS Surgical System, appeared on the market at similar times. The parent company of da Vinci, Intuitive Surgical, acquired the intellectual property rights to the ZEUS system and discontinued the product. As a result, only the da Vinci Robotic Surgical System is available for use today ( Fig. 71.2 ).
Eventually, high-definition, three-dimensional cameras were added to robots, allowing surgeons to explore a patient’s anatomy and access traditionally difficult-to-reach surgical sites from a console located next to the operating table. While several robotic companies have developed products, at the moment, only two remain: AESOP and da Vinci.
The da Vinci robot has four components ( Figs. 71.2 and 71.3 ):
Surgeon console ( Figs. 71.4 to 71.6 )
EndoWrist instruments ( Figs. 71.7 and 71.8 )
Optical vision cart
Patient cart with four movable arms ( Fig. 71.9 )
The surgeon sits at the surgeon console (see Figs. 71.4 and 71.5 ) and remotely controls the EndoWrist instruments that are attached to the patient cart. Anesthesia personnel, surgical assistants, and circulating nursing staff may see the procedure in real time via the screen on the optical vision cart (see Fig. 71.2 ).
During an operation, the surgeon views two high-definition monitors that mimic a binocular or microscope. This two-monitor view creates three-dimensional images. The surgeon’s arms rest on the master controls, and his/her fingers manipulate the levers that control EndoWrist articulation. Foot pedals control electrocautery, movement of the robotic camera, and disengagement of robotic instruments. To facilitate collaboration and training, the da Vinci machine will often have two consoles allowing two surgeons to participate in the patient’s care.
The robot is preferred to open procedures because it allows a minimally invasive approach to surgical pathologies. Less tissue manipulation leads to fewer adhesions and potentially faster recovery from surgery. Fewer wound complications, including infections and incisional hernias, and shorter hospitalizations make robotic surgery attractive when compared to other minimally invasive or open techniques. Further, the robotic approach to surgical procedures allows discrete movements that are helpful in microsurgical dissection and re-attachment of tissues. In comparison with human arms, robotic arms permit seven degrees of free movement. These movements can be categorized into: gross arm movement by the da Vinci robot, fine movements by the articulating arms, and surgical actions performed by the articulating arms ( Table 71.1 , Figs. 71.7 and 71.8 ).
Gross Arm Movements | Wrist Movements | Surgical Actions |
---|---|---|
In and out | Yaw (side-to-side and left-right) | Grasp or cut |
Up and down | Pitch (up and down) | |
Side-to-side | Rotation and roll |
These articulating arms are not limited by constraints associated with human wrist joints. Additionally, the robot allows for larger, more coarse movements to be miniaturized in the operating field. For example, moving the controls by 5 mm may move the articulating arms by only 1 mm. This miniaturization permits more fine control. Furthermore, robotic software can reduce or eliminate hand tremors, thereby improving the safety and precision of surgery.
The robot is used in hysterectomy, prostatectomy, nephrectomy, cardiac surgery, colectomy, general laparoscopic, thoracoscopic, and transoral otolaryngologic procedures. Although most procedures performed using the da Vinci robot are urologic (prostatectomy) and gynecologic (hysterectomy), a wide range of new applications are being discovered.
Essentially, robotic surgery is helpful whenever microsurgery is necessary and the target organ is difficult to reach. It is especially valuable if its usage converts what is traditionally an open procedure to a minimally invasive procedure.
As imaging modalities and artificial intelligence are applied to robotic surgery, the field will evolve. It is probable that nonrigid, flexible articulating arms of progressively smaller size will ultimately replace the current, rigid articulating arms. “Snake-like” articulating arms will facilitate fewer and smaller incisions to be made in a patient and allow less invasive, perhaps even scar-free, surgery to be performed. Finally, as artificial intelligence evolves, it is possible that semi-autonomous robotic surgery will develop with computer algorithms guiding surgical instruments.
There have been reports of successful robotic intubations. The Kepler Intubation System (KIS), developed by Thomas Hemmerling, has been shown to intubate mannequins successfully by an operator who has either a direct or indirect view of the patient. KIS is a low-cost system consisting of a joystick, a robot arm, the Pentax videolaryngoscope, and a software control. The intubations occurred within 40 to 60 seconds with a 100% success rate on the first attempt. This system also allowed for semiautomated (a computer system replayed prior operator driven movement sequences) intubations that occurred in less than 45 seconds and had a 100% success rate. The system has also been used on 12 patients and was successful with a first-pass intubation in 11 of the 12 patients (1 was unable to be completed due to fogging of the equipment). The intubations were done in approximately 93 seconds. It remains to be seen if a robot intubation system will have widespread use. However, it may have applications in settings where it would be difficult to transport a trained anesthesia provider to the location, such as deep space exploration.
Robotic surgery causes a number of physiologic changes. Positioning, insufflation with carbon dioxide (CO 2 ) to allow visualization of the surgical field, and physiologic changes associated with increasing intracompartmental pressure (i.e., abdominal, thoracic, or oral) are all seen with robotic surgery. Therefore, it is imperative that anesthesia providers are aware of these perturbations so that appropriate compensatory plans may be created.
Except for otolaryngological procedures, inert gas must be insufflated into a patient’s body to visualize the surgical field. CO 2 is the inert gas of choice because it has a high diffusion coefficient and the risk of a gas emboli is minimized since CO 2 is easily excreted from the body through the respiratory system. As CO 2 is insufflated into the abdomen, surgeons exercise caution to keep intraabdominal pressures below 20 cm of water. By minimizing intraperitoneal pressure, the vagal stimulation from elevated intraabdominal pressure is minimized. However, if the patient has a particularly pronounced resting vagal tone or a significant vagal response to peritoneal insufflation, pharmacologic intervention by the anesthesia provider or reduction of pneumoperitoneum may be necessary.
Insufflating the surgical site with CO 2 also may lead to sudden increases in CO 2 in the blood stream because it is absorbed from lymphatic and venous plexi. As a result, increasing minute ventilation is necessary to maintain normocarbia and to keep the patient in homeostasis.
Another potential untoward effect of CO 2 insufflation is gas embolism. Although rare, a gas embolus may have catastrophic effects on the cardiopulmonary system if the embolus becomes lodged in the pulmonary system. Additionally, if a patient has an atrioseptal or ventriculoseptal defect, he or she may develop a gas embolus in the cerebrovasculature with potentially devastating complications.
A more common and less devastating complication of gas insufflation and increased intraperitoneal pressure is atelectasis. This is exacerbated by the effects of insufflation on diaphragmatic excursion. CO 2 insufflation may lead to pneumomediastinum or subcutaneous emphysema (incidence of 0.43%-2.3%). Although this finding typically has no clinical consequences, it may be associated with prolonged CO 2 excretion postoperatively causing hypercarbia and acidosis. Also, there have been reported cases of pneumothorax caused by extension of insufflated gas through diaphragmatic congenital channels into pleural cavities (incidence of 0.03%). An increased incidence is associated with an increased number and size of trocars, longer surgical time, higher gas flow rate, intensified gas pressure, loose trocars, and difficult trocar placement. Due to a number of factors, such as lack of external visualization and haptic feedback during robotic surgery, there is an increased incidence of gas extravasation.
Pulmonary vasoconstriction results from insufflation due to:
CO 2 absorption, and
physical compression of the lungs.
CO 2 absorption results in hypercarbia and acidosis. The pulmonary system’s response to hypercarbia is vasoconstriction, in order to preserve gas exchange by preferentially shunting blood away from less ventilated portions of the lungs. Therefore, carbon dioxide insufflation has a vasoconstricting effect on the pulmonary vasculature.
In addition, during robotic surgery, pneumoperitoneum results in compression atelectasis as the intrathoracic pressure competes with elevated intraperitoneal pressures resulting in lung tissue compression. This process is worsened by Trendelenburg positioning. Nasogastric or orogastric tubes may facilitate gastric decompression and help reduce, albeit not eliminate, increased intraabdominal pressures. As functional residual capacity decreases, patients may experience increased lung collapse and atelectasis. This phenomenon combined with the vasoconstriction due to the CO 2 insufflation increases the ventilation/perfusion mismatch. This mismatch results in decreased oxygenation.
Atelectasis also leads to hypoxic pulmonary vasoconstriction (HPV). HPV is a compensatory mechanism that allows the body to preferentially divert blood from oxygen-poor regions of the lungs to oxygen-rich regions. and improves gas exchange by shunting blood to areas of the lung that are ventilating normally. This effect appears to be caused by mitochondrial sensors inspiring voltage-gated calcium channels to increase the cytosolic calcium, thereby leading to vasoconstriction.
Insufflating the peritoneum also decreases respiratory compliance and elevates airway pressures. This process makes ventilation increasingly difficult and worsens the aforementioned hypercarbia. To improve ventilation it has been recommended to switch mode from volume control ventilation to pressure control ventilation (PCV). However it has been shown in a randomized trial of patients for robot-assisted laparoscopic radical prostatectomy that aside from lower peak airway pressures and improved compliance in the PCV mode, there was no benefit in other parameters, such as: central venous pressure, mean pulmonary arterial pressure, pulmonary capillary wedge pressure, cardiac index, arterial oxygen pressure, mean airway pressure, physiological dead space, and intrapulmonary shunt fraction.
Elevated CO 2 levels also shift the oxyhemoglobin dissociation curve to the right via the Haldane effect. This shift in the dissociation curve helps deliver oxygen to the tissues and results in slightly less ischemia than would be expected. A potential explanation for this phenomenon is that carbon dioxide inspires the Haldane effect and HPV.
Increased absorbed CO 2 from insufflation also leads to cerebrovascular dilation. Although CO 2 leads to blood being preferentially shunted away from the pulmonary vasculature, CO 2 in the cerebral circulation leads to cerebral vascular dilation. Anesthesiologists must be mindful of the potential increase in intracranial pressure (ICP) that may arise from elevated CO 2 levels. Additionally, a number of robotic procedures require steep Trendelenburg positioning to allow surgical visualization of pelvic structures, which also results in increased ICP. Anesthesiologists must be cognizant of possible increased ICP especially in cases where patients need a ventriculoperitoneal shunt due to baseline increases in ICP.
Hypercapnia will lead to a respiratory acidosis as CO 2 is combined with water and is metabolized into bicarbonate and hydrogen ions. Since bicarbonate does not effectively buffer the acidosis induced from hypercarbia, a respiratory acidosis occurs.
Hypercapnia will augment anesthetic effects. Acute hypercapnia will also result in depressed consciousness when PaCO 2 exceeds 80 mm Hg. Increased CO 2 also decreases myocyte contractility and can potentially increase the myocardial susceptibility to arrhythmias.
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