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Breast imaging is integral to the diagnosis and evaluation of breast cancer and other breast pathologies. While ultrasound and magnetic resonance radiology (MRI) also play important roles, mammography is often considered the foundation or workhorse of breast radiology. Mammography is versatile with ubiquitous roles in breast imaging, including breast cancer screening, diagnostic evaluation, and procedural guidance. It is an efficient method for evaluation of the entire breast and offers excellent visualization and characterization of breast calcifications.
Screening mammography is key to early breast cancer detection. Breast cancer is the most common non–skin-related malignancy among women, affecting approximately one in eight women in the United States. It is also the second leading cause of cancer-related death in women and the leading cause of cancer-related death in women younger than 60 years old. Screening mammography has been consistently shown to be a cost-effective screening modality and is the only screening test that has been shown in randomized controlled trials to significantly reduce breast cancer mortality. As a result, mammography is a staple in modern medicine preventative care.
Refined by decades of technological advancements and now assisted by complementary ultrasound and MRI, mammography serves as an essential tool in the breast imager’s toolbox. This chapter will cover the basics of standard two-dimensional (2D) digital mammography. Subsequent chapters will provide more in-depth review of specific applications of mammography, including a chapter devoted to tomosynthesis.
When a mammogram is performed, each breast is placed on a support plate and compressed by parallel compression plates. Breast compression spreads superimposed normal parenchymal tissue for better visualization of underlying lesions ( Box 1.1 ). Breast thickness is decreased by compression, thereby decreasing the radiation dose to the breast. Compression helps achieve more uniform thickness throughout the breast to avoid overexposure of the thinner anterior breast and underexposure of the thicker posterior breast. It reduces geometric blur by reducing the distance between the breast tissue and the image receptor. Compression improves image contrast by reducing scatter production and allowing for selection of lower energy (kV) x-rays. Compression also immobilizes the breast and decreases exposure time, minimizing image blurring due to motion.
Reduces parenchymal superimposition for better visualization
Decreases radiation dose
Ensures adequate x-ray penetration throughout the breast
Reduces image blurring by decreasing patient motion and exposure time
Reduces geometric blur and improves spatial resolution by reducing the distance between the breast tissue and the image receptor
Improves image contrast by reducing scatter production and allowing selection of lower kV x-rays
Patients may experience breast pain during compression. Methods to mitigate patient discomfort include performing the mammogram during day 7 to 10 of the menstrual cycle, adding foam padding between the breast and compression plates, and taking analgesics prior to receiving the mammogram.
The routine mammogram consists of two complementary standard views for each breast: the craniocaudal (CC) view and the mediolateral oblique (MLO) view ( Table 1.1 ). Based on standard mammographic terminology, each projection describes the direction of the x-ray beam. The first letter in the projection refers to the location of the x-ray source and the second refers to the location of the image receptor. For example, in the CC view the x-ray beam travels superior to inferior, from the cranial to caudal direction.
Area of Interest | View | Abbreviation |
---|---|---|
Retroareolar | Spot compression with nipple in profile | – |
Outer breast | Laterally exaggerated craniocaudal | XCCL |
Inner breast | Medially exaggerated craniocaudal | XCCM |
Cleavage | CV | |
Upper breast | Craniocaudal (CC) from below | CCFB |
|
Superior-inferior oblique | SIO |
When performing the CC view, the patient faces toward the mammography unit, and the image receptor is placed inferior to the breast. The inferior breast is relatively mobile and allows the inframammary fold to be elevated when the technologist lifts and pulls the breast forward onto the positioning platform. This maneuver allows greater visualization of the posterior and superior breast tissue. The breast is then compressed in the axial plane, perpendicular to the x-ray beam ( Fig. 1.1 ). The CC view includes most of the breast tissue except for the far lateral and far posterior breast.
In the MLO projection, the x-ray beam travels from superomedial to inferolateral. The breast compression plane is along the angulation of underlying pectoralis major muscle, usually at 45 degrees ( Fig. 1.2 ). However, angulation of the compression plane varies with patient anatomy and may range from 40 to 60 degrees; thinner body habitus may need a slightly steeper obliquity, and shorter or heavier body habitus may need a slightly flatter obliquity. The course of the pectoralis muscle can be approximated by drawing an imaginary line between the ipsilateral shoulder to the mid sternum. When properly positioned, the MLO view includes nearly the entire breast including the axillary tail.
These two standard views are complementary. The MLO view visualizes the most amount of breast tissue. It is the best for viewing the posterior, upper-outer quadrant, axillary tail, and lower-inner quadrant of the breast. However, there may be considerable breast tissue overlap, often with limited compression of the more anterior structures. Also, the far superior-medial breast tissue (upper-inner quadrant) may sometimes be excluded from the MLO view. The CC view allows for better visualization of the medial and posteromedial tissue, as well as better compression of the subareolar and central breast.
Standardized image labeling is important for consistency, allowing mammograms to be accurately identified and interpreted even outside of the performing institution. According to the Mammography Quality Standards Act (MQSA), the patient identification label is required to include the patient’s name, unique identification number and/or date of birth, facility name and location, examination date, technologist’s initials, cassette (screen) number for screen-film and computed radiography images, and mammographic unit identification (if there is more than one unit in the facility) ( Box 1.2 ). The view and laterality label should be placed near the axilla on all mammograms. The laterality should be listed first, followed by technique (e.g., magnification, implant displacement) and projection (e.g., CC).
Patient name
Unique identification number and/or date of birth
Facility name and location
Examination date
Technologist’s initials
Cassette/screen identification (for screen film or computed radiography; not for digital mammography)
Mammographic unit (if there is more than one unit)
Laterality and view placed near axilla
Before interpreting a mammogram, it is important to first assess whether the mammogram is technically adequate ( Box 1.3 ). Suboptimal image quality compromises mammographic evaluation and may lead to missed cancers.
Compression: Look for adequate compression with dispersion of breast tissue
Contrast: There should be sufficient contrast to differentiate breast tissues
Exposure: Look for adequate exposure throughout the breast
Sharpness: Check that the breast trabeculae and skin edge are sharp and free of motion
Noise: Noise should be minimized as it can interfere with detection of small findings such as microcalcification
Artifacts: Images should be free of artifacts, which may obscure or mimic pathology
Motion
Hair
Skin folds
Antiperspirant
Chin or other body parts
Grid lines
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