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T-Cell and Natural Killer–Cell Neoplasms With Primarily Leukemic Involvement T-Cell Prolymphocytic Leukemia Overview and Incidence T-cell prolymphocytic leukemia (T-PLL) is an aggressive, mature T-cell malignancy affecting predominantly older adults and accounts for 2% of chronic leukemias. There is an approximate…
General Approach A great number of changes occur in the bone marrow during and after therapy for malignancy. Although proper interpretation of these changes requires knowledge of the patient's original disease process, some general features are common to all cases.…