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Psoriasis and Systemic Disease
Key Points Psoriasis is common, affecting over 125 million worldwide. Comorbidities include diabetes, hypertension, dyslipidemia, obesity, myocardial infarction, stroke, cardiovascular death, lymphoma, autoimmune disorders, and renal disease. TNF signaling and the IL-23/Th17 pathways are critical in the pathogenesis of psoriasis,…