Tag Jerrold Lerman

Malignant Hyperthermia

MALIGNANT HYPERTHERMIA (MH) is a pharmacogenetic disease of skeletal muscle that may precipitate a potentially fatal sequence of metabolic responses in the presence of triggering anesthetics. The primary triggers for MH—inhalational anesthetics and succinylcholine—induce an uncontrollable release of intramyoplasmic calcium…