The management of hematological issues in surgical patients can be challenging due to myriad factors. Bleeding and thrombotic issues may be present concurrently, and the impact of underlying pathological issues may be masked by the primary pathology warranting surgery. Nevertheless,…
Acute coronary syndrome (ACS) leads to millions of hospital admissions worldwide each year and is a leading cause of death. Antithrombotic therapies are a cornerstone in the immediate and long-term management of ACS, reducing the risk of myocardial infarction (MI)…
Arterial or venous thromboembolism is a major cause of morbidity and mortality. Arterial thrombosis is the most common cause of acute myocardial infarction, ischemic stroke, and limb gangrene, whereas deep vein thrombosis can lead to pulmonary embolism, which can be…
Venous thromboembolism (VTE) encompasses deep vein thrombosis (DVT) and pulmonary embolism (PE). DVT commonly affects the deep veins of the legs, and infrequently involves veins at other anatomical sites (such as upper extremity, splanchnic, or cerebral veins). Thrombotic occlusion of…
Arterial and venous thromboses are common problems for all clinicians. Some patients with thrombosis have an underlying hypercoagulable state. These hypercoagulable states can be divided into three categories: inherited disorders, acquired disorders, and those that are mixed in origin. Inherited…
Blood is the principal vehicle delivering oxygen and nutrients to the various tissues and organs of the body. Blood flow and the integrity of the vasculature are essential to life itself. The hemostatic process has evolved to provide damage recognition…
Introduction Hemostasis preserves vascular integrity by balancing the physiologic processes that maintain blood in a fluid state under normal circumstances and prevent excessive bleeding after vascular injury. Preservation of blood fluidity depends on an intact vascular endothelium, and a complex…
Introduction Arterial and venous thromboses are major causes of morbidity and mortality. Arterial thrombosis is the most common cause of acute myocardial infarction (MI), ischemic stroke, and limb gangrene, whereas deep vein thrombosis can lead to pulmonary embolism, which can…
The management of hematological issues in surgical patients can be challenging due to myriad factors. Bleeding and thrombotic issues may be present concurrently, and the impact of underlying pathological issues may be masked by the primary pathology warranting surgery. Nevertheless,…
Acute coronary syndrome (ACS) leads to millions of hospital admissions worldwide each year and is a leading cause of death. Antithrombotic therapies are a cornerstone in the immediate and long-term management of ACS, reducing the risk of myocardial infarction (MI)…