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Abstract Background One of the defining achievements of the early 21st century is the sequencing and alignment of more than 90% of the human genome. Of course, there is not a single human genome: individuals differ from each other by…
Abstract Background Nucleic acid techniques as applied to molecular diagnostics have enabled the laboratorian to modify, amplify, detect, discriminate, and sequence nucleic acids with levels of sensitivity and specificity unparalleled by other laboratory techniques. Molecular diagnostic techniques continue to produce…
Abstract Background Automation has dramatically changed both the analytical and nonanalytical aspects of clinical laboratory operations. Automation of laboratory test procedures began more than 50 years ago, but nonanalytical automation—including conveyor systems, interfaced analyzers, and automated specimen processing and storage—began…
Abstract Background Laboratory medicine is a complex field that measures biomarkers and microorganisms in bodily specimens or tissues to diagnose and manage diseases. It encompasses multiple disciplines including clinical chemistry, hematology and coagulation, clinical microbiology, clinical immunology, molecular diagnostics, and…