Tag Carl T. Wittwer

Nucleic acid techniques

Abstract Background Nucleic acid techniques as applied to molecular diagnostics have enabled the laboratorian to modify, amplify, detect, discriminate, and sequence nucleic acids with levels of sensitivity and specificity unparalleled by other laboratory techniques. Molecular diagnostic techniques continue to produce…

Automation in the clinical laboratory

Abstract Background Automation has dramatically changed both the analytical and nonanalytical aspects of clinical laboratory operations. Automation of laboratory test procedures began more than 50 years ago, but nonanalytical automation—including conveyor systems, interfaced analyzers, and automated specimen processing and storage—began…

Laboratory medicine

Abstract Background Laboratory medicine is a complex field that measures biomarkers and microorganisms in bodily specimens or tissues to diagnose and manage diseases. It encompasses multiple disciplines including clinical chemistry, hematology and coagulation, clinical microbiology, clinical immunology, molecular diagnostics, and…