Melanoma Clinical features Over the last several decades, the conspicuous increasing incidence of this malignant neoplasm has made this disease more prominent, linked to some rise in morbidity and mortality. While roughly half of the major cancers in the United…
Ephelide Clinical features Ephelides (freckles) are extremely common lesions that present as clusters of small (approximately 2.0 mm in diameter), uniformly pigmented macules ( Fig. 25.1 ). They are directly related to exposure to sunlight and are much more conspicuous in…
Specimen fixation, grossing/put-through, processing, embedding and sectioning The aim of fixation is to maintain clear and consistent lesional features and to preserve tissue in an optimal state suitable for a range of staining and ancillary histopathological techniques. Most fixation methods…