Tag Anil V. Parwani MD PhD MBA

Paratesticular leiomyosarcoma

Definition A rare malignant mesenchymal tumor of smooth muscle differentiation Clinical features Epidemiology Second most common paratesticular sarcoma in adults Most commonly arising from the spermatic cord, but may also arise from the epididymis and testicular tunics Wide age range,…

Paratesticular lipoma

Definition Benign tumor comprising mature adipocytes of the paratesticular region Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here

Paratesticular idiopathic smooth muscle hyperplasia

Definition Haphazard nonneoplastic overgrowth of the native smooth muscle between or around the vessels or efferent ducts in the paratesticular region or the spermatic cord Clinical features Epidemiology Mean age, 63 years (range, 46–81 years) Etiology not clear; may represent…

Spermatocytic tumor

Definition Spermatocytic tumor, formerly known as spermatocytic seminoma, is a rare germ cell tumor distinct from classical seminoma both clinically and pathologically. Pathologically, it is characterized by three distinct cell types, lack of cytoplasmic glycogen, and scant to absent lymphocytic…

Primary renal synovial sarcoma

Definition An extremely rare spindle cell tumor with rare epithelial differentiation and the characteristic translocation t(X;18)(p11.2;q11) Clinical features Epidemiology Wide age range (15–71 years), with a mean age of 39 years No sex predilection; male-to-female ratio, 1:1 You’re Reading a Preview…

Nephrogenic rests and nephroblastomatosis

Definition Nephrogenic rests are abnormally persistent embryonal cells beyond 36 weeks of gestation and are associated with and capable of developing into nephroblastomas (Wilms tumor). Nephroblastomatosis is defined as the presence of diffuse and multifocal nephrogenic rests. Clinical features Epidemiology…

Renal cell carcinoma, unclassified type

Definition A group of renal cell carcinomas (RCCs) whose morphology or growth pattern does not readily fit any of the RCC subtypes recognized by the current World Health Organization classification Clinical features Epidemiology Represents 3%–5% of all RCCs The incidence…

Chromophobe renal cell carcinoma

Definition A renal cell carcinoma (RCC) subtype comprising large pale and/or eosinophilic cells with prominent cell borders, irregular nuclei, and perineuclear halos Clinical features Epidemiology Five percent of RCCs Mean age, 50–60 years (range, 30–90 years) Male-to-female ratio, 1.5:1 You’re…

Xanthogranulomatous pyelonephritis

Definition A destructive granulomatous inflammatory process of renal parenchyma as the result of long-term urinary tract obstruction and infection Clinical features Epidemiology Seventy percent of patients are female. Ages range widely, from newborn to elderly. Urine cultures most frequently show…