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Definition and Background Among the heterogeneous group of hematopoietic neoplasms with a predominant population of large cells, Stein and colleagues recognized a subgroup of tumors with large cells exhibiting bizarre morphologic features and prominent sinusoidal invasion and expressing the Ki-1…
Definition The World Health Organization (WHO) recognizes nodular lymphocyte–predominant Hodgkin's lymphoma (NLPHL) as a separate entity distinct from classical Hodgkin's lymphoma (CHL) in the WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. This reflects the fact that there are…