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Introduction Melanoma is the fastest growing malignancy in the United States in terms of incidence. In the year 2015, it is estimated that 73,870 men and women will be diagnosed with cutaneous melanoma in the United States and that 9940…
Key Points Chemotherapy regimens, non-specific immunostimulants and vaccines alone have failed to show any survival benefit in the adjuvant setting. High-dose interferon-α2b is the only approved drug shown to improve relapse-free and overall survival in large multi-institutional randomized controlled trials…