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Case 1.1 1. b is correct. The circulation time will be shortened because some blood passes through the shunt (short circuit). Case 2.1 1. c is correct. When the extracellular K + concentration increases, the Nernst equation indicates that the…
Objectives 1. Describe the sequence of cardiovascular events during exercise. 2. Describe how most cardiovascular functions are integrated in exercise. 3. Describe the effects of blood loss on the cardiovascular system. 4. Explain the various compensatory mechanisms that protect against…
Objectives 1. Describe the regulation of cutaneous blood flow and its role in maintaining a constant body temperature. 2. Indicate the relative importance of the local and neural factors in adjustments of skeletal muscle blood flow at rest and during…
Objectives 1. Delineate the physical, neural, and metabolic factors that affect coronary blood flow. 2. Explain the relative importance of these factors in the regulation of the coronary circulation. 3. Compare the oxygen requirements of the heart during pressure work…
Objectives 1. Describe the principal determinants of cardiac output. 2. Describe the principal determinants of cardiac preload and afterload. 3. Explain the mechanical coupling between the heart and blood vessels. 4. Explain the effects of gravity on venous function and…
Objectives 1. Indicate the intrinsic and extrinsic (neural and humoral) factors that regulate peripheral blood flow. 2. Explain autoregulation of blood flow and the myogenic mechanism for local adjustments of blood flow. 3. Elucidate metabolic regulation of blood flow. 4.…
Objectives 1. Describe the regulation of regional blood flow by the arterioles. 2. Enumerate the physical and chemical factors that affect the microvessels. 3. Explain the roles of diffusion, filtration, and pinocytosis in transcapillary exchange. 4. Describe the balance between…
Objectives 1. Explain how the pulsatile blood flow in the large arteries is converted into a steady flow in the capillaries. 2. Discuss arterial compliance and its relation to stroke volume and pulse pressure. 3. Explain the factors that determine…
Objectives 1. Define the relationship between the velocity of blood flow and vascular cross-sectional area. 2. Describe the factors that govern the relationship between blood flow and pressure gradient. 3. Distinguish between resistances in series and resistances in parallel. 4.…