Reoperative Cardiac Surgery


Key Points

  • 1.

    Reoperative cardiac surgery presents greater risk than first-time surgery because patients are usually older, have more comorbidity, and have more advanced cardiovascular disease. Also, resternotomy can be hazardous due to adhesions of cardiac structures to the sternum. Bypass conduits may not be available owing to prior use, and the frequency of valve replacement versus valve repair is higher.

  • 2.

    A thorough history, clinical evaluation, and review of imaging must be performed—with particular thought to weighing the risk of surgery against the possibility of medical management with multidisciplinary expertise—before making the decision to proceed.

  • 3.

    Preinduction anesthestic preparations include placement of defibrillator pads, pacemaker or defibrillator adjustments, and placement of invasive monitoring in the setting of the possibility of peripheral cannulation strategies and alternative cardiopulmonary bypass techniques such as cooling before sternotomy.

  • 4.

    Emergency reexploration is a high-risk situation in which expedited surgical intervention is required, usually in the setting of bleeding with pericardial tamponade. Transfusion should be anticipated, hemodynamics supported, and heparin ready to administer in anticipation of possible cardiopulmonary bypass.

In contemporary practice, 3% to 4% of coronary artery bypass graft (CABG) operations and approximately 10% of valve surgery procedures are reoperations. Reoperative cardiac surgery carries an incremental risk of mortality and major morbidity compared with first-time or primary cardiac surgery because patients are usually older, with additional comorbidity and more advanced cardiac disease, and because of specific technical challenges presented by prior cardiac surgery. The surgical approach to incision and cannulation in coronary and valve surgery reoperations often differs significantly from the approach used in primary cases, and adverse intraoperative events that require immediate changes to the planned strategy are common and often predictable. Preoperative assessment and planning with the surgical team is therefore particularly important because optimal patient care may require the modification of several aspects of standardized cardiac anesthetic approaches. The incidence of emergency reexploration ranges from 1% to 5% after cardiac surgery, and the primary challenges relate to effectively managing major cardiopulmonary instability and ensuring safe and efficient surgery, either in the operating room or outside the operating room setting.

Reoperative Cardiac Surgery

Indications for Reoperative Cardiac Surgery

The indications for reoperative cardiac surgery are based on the same principles as for primary cardiac surgery. However, the incremental hazard of resternotomy, the lack of bypass conduits, the greater age and comorbidity of this patient group, and the likelihood of valve replacement rather than repair are additional considerations. Consequently, the threshold for recommending surgery rather than medical or transcatheter approaches is higher for reoperative patients. Most patients with symptomatic coronary artery or graft stenoses after CABG surgery are most effectively treated by percutaneous coronary intervention (PCI). Very symptomatic patients with significant lesions to a left anterior descending graft are generally considered to gain symptomatic and prognostic benefit from reoperative coronary artery surgery. The main indications for reoperative valve surgery include prosthetic valve dysfunction (for which the results of transcatheter valve-in-valve implantation are still preliminary) and endocarditis, which is a contraindication to transcatheter valve replacement. Paravalvular leaks are increasingly addressed by percutaneous placement of occluder devices. Late reoperation for isolated severe tricuspid regurgitation is associated with particularly high mortality and major morbidity because of the high prevalence of preoperative moderate-to-severe right ventricular dysfunction, pulmonary arterial hypertension, and multiorgan dysfunction in this population.

Preoperative Assessment

History

Patients undergoing reoperative cardiac surgery are generally older, have more comorbidity, and more advanced cardiovascular disease than patients undergoing first-time surgery. The decision to operate usually depends on correlating a precise account of the nature, timing, and severity of symptoms with the findings from diagnostic studies and balancing the benefits of intervention against the incremental risk of mortality and morbidity posed by reoperation. Additionally, the medical history should establish details of all prior cardiovascular procedures, including date and type of PCI; any previous cardiac surgery, including incisions; history of difficult intubation or adverse reaction to anesthesia, respiratory failure, or tracheostomy; coagulopathy and blood transfusions; and postoperative sepsis and organ dysfunction. Although the balance of risks generally favors continuing antiplatelet medication until surgery in non-reoperative patients, this may not be the case in patients scheduled for reoperative surgery, who will be at greater risk of postoperative coagulopathy and bleeding. It may be appropriate to admit patients preoperatively to discontinue oral anticoagulation and transition to a shorter-acting regimen, such as a heparin infusion.

Clinical Examination

One of the most important risk factors for poor outcomes is frailty. Although this is not well defined, and consequently is not included in most risk models, it is a relatively easy, albeit subjective, judgment often made by looking at a patient. Physical examination of all patients referred for cardiac surgery includes a careful inspection of the entire chest and abdomen. Patients may omit to mention distant cardiac and thoracic surgery procedures, and these may become evident only from incisions, which can be inframammary, posterior thoracotomy, or axillary. All incisions, including conduit harvest sites, pacemaker or defibrillator insertion sites, and potential sites of peripheral cannulation for cardiopulmonary bypass (CPB) in upper and lower extremities, should be assessed for signs of distant or recent infection, poor healing, and vascular complications such as stenosis or aneurysm formation. Evaluation of the airway includes inspection of the suprasternal notch and trachea for evidence of prior tracheostomy.

Imaging

With the exception of young adult patients without risk factors for acquired or congenital coronary artery disease, all patients should have recent cardiac catheterization, including coronary angiography, to assess the patency and anatomy of native vessels and any CABG. In young patients, computed tomographic (CT) coronary angiography usually provides sufficient information about coronary anatomy. Coronary angiograms should be reviewed to determine whether grafts are close or even adherent to the sternum.

Noncontrast computed tomography provides helpful visualization of calcification and aneurysmal segments along the entire arterial tree from aortic root to femoral vessels that may dictate choice of cannulation site. The presence of large amounts of prosthetic material indicates potentially severe adhesions. Intravenous contrast may be employed in CT angiography to demonstrate the course of bypass grafts more clearly; contrast is required to assess patency, and it provides detailed information on the presence of peripheral vascular disease, which is particularly relevant if peripheral arterial cannulation is planned or the patient is likely to need an intraaortic balloon pump.

Echocardiography is necessary to quantify right and left ventricular function, the presence of pulmonary hypertension, and the nature and grade of any valvular dysfunction. Transesophageal echocardiography (TEE) is particularly valuable in the detailed assessment of prosthetic valve endocarditis and failed valve repair or if transthoracic echocardiographic windows are poor.

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