Prostatic carcinoma, atrophic variant


Definition

  • The variant of prostatic adenocarcinoma with cancer glands having a scant volume of cytoplasm, which can be mistaken for atrophy or postatrophic hyperplasia.

Clinical features

Epidemiology

  • Two percent incidence in needle core cases, 16% incidence in radical prostatectomy specimens

  • Mixed with usual-type prostatic adenocarcinoma and comprises 16%–25% of the total tumor volume on average (range: 10%–90% in needle biopsies, 1%–70% in prostatectomies)

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