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Chorioangiomas are the most common histologic type of placental tumor. They are usually well circumscribed, vascular, and predominantly hypoechoic, ranging from microscopic to several centimeters in diameter.
Chorioangiomas are found in 0.5% to 1% of placentas examined at delivery. Microangiomas are the most common but are less likely to cause any fetal or maternal complications and will often go undetected. Masses greater than 5 cm, also known as larger or giant chorioangiomas, however, are found in 1 : 10,000 to 3 : 10,000 pregnancies.
Histologically, there are two main types of chorioangiomas: angiomatous (formed from numerous blood vessels), and cellular (formed by loose mesenchymal tissue). Large tumors often contain degenerative changes such as necrosis, calcification, and myxoid changes. They are formed by excessive proliferation of blood vessels in chorionic villi and are perfused by the fetal circulation. The size, therefore, determines the amount of fetal blood that is sequestered within the tumor and increases the risk for fetal complications.
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