Rosai and Ackerman's Surgical Pathology

Small Bowel

Normal Anatomy The small bowel extends from the pylorus to the ileocecal valve and measures approximately 6–7 m in length in adults. It is divided into three portions: duodenum , jejunum , and ileum . The ligament of Treitz is the…

Stomach

Normal Anatomy The stomach is divided into the following regions: cardia , fundus , corpus or body , antrum , and pylorus . The superomedial margin is termed the lesser curvature , and the inferolateral margin is termed the greater…

Esophagus

Normal Anatomy of the Esophagus The esophagus is a muscular tubular structure that measures approximately 25 cm in adult individuals and extends from the cricopharyngeal muscle, which forms the upper esophageal sphincter (at the level of the sixth cervical vertebra, about…

Mediastinum

Generalities The mediastinum is the portion of the thoracic cavity located between the pleural cavities, extending anteroposteriorly from the sternum to the spine and from the thoracic inlet superiorly to the diaphragm inferiorly. The numerous organs and structures it contains…

Pleura

Normal Anatomy of the Pleura Both the visceral and parietal pleural layers have a lining of mesothelial cells endowed with a continuous basement membrane and resting on a layer of well-vascularized fibroelastic connective tissue matrix. The submesothelial connective tissue is…

Lung

Normal Anatomy Grossly the lungs are subdivided into lobes, three on the right (upper, middle, and lower) and two on the left (upper and lower). Each lobe is supplied by a dedicated lobar bronchus with a companion artery and vein…

Parathyroid Glands

Normal Gross Anatomy and Embryology The parathyroid glands, the last major organ to be recognized in humans, were discovered in 1880 by Ivar Sandstrom, a Swedish medical student, as recounted by Aidan Carney in his delightful essay on the subject.…

Thyroid Gland

Normal Anatomy and Thyroid Gland Development The thyroid anlage appears in the embryo as a midline structure at the site corresponding to the foramen cecum of the adult tongue. From here, it descends as a component of the thyroglossal duct…

Ear

Introduction Nearly all the diseases that can involve the ear also occur in other sites of the body. However, some of these diseases either have a predilection for the ear or pose special problems when occurring at this site. Only…

Major and Minor Salivary Glands

Normal Anatomy The major salivary glands are the paired parotid, submandibular (submaxillary), and sublingual glands. The parotid gland weighs 14–28 g, the submandibular gland weighs 7–8 g, and the sublingual gland weighs 3 g. The main duct of the parotid gland (Stensen duct)…