16.1 Introduction Intensity-modulated radiotherapy (IMRT) provides exceptional control over the delivery of dose. Figure 16.1 shows an example of a 7-field IMRT plan for a patient with T3 oropharyngeal carcinoma of the head and neck. This case illustrates the ability…
15.1 Introduction Electron beams have been used in radiotherapy since the 1940s but did not gain widespread use until the 1970s with the commercial development of linear accelerators (linacs). Electrons lose energy as they traverse a medium through various elastic…
14.1 Introduction The overall goal of the treatment planning process is to produce the optimal dose distribution for the patient, taking into account the following factors: 1. Treatment intent (curative or palliative) 2. Stage of disease (extent of involvement) 3.…
13.1 Introduction Prior to the early 1990s, “simulation” for an external beam radiotherapy consisted of just that: simulating the treatment with a device that mimicked a linear accelerator (linac) in all aspects except the delivery of a therapeutic beam. These…
12.1 Introduction Watershed Accidents in Radiation Oncology One way to view the issue of quality and safety in radiotherapy is to consider the serious accidents that have garnered the attention of the community and occasionally the media. The purpose of…
11.1 Introduction Information technology (IT) in Radiation Oncology has developed into highly complex networks driving much of treatment delivery and other safety-critical tasks in the department. Based on the size of a Radiation Oncology clinic, the role of the physicist…
10.1 Introduction The National Council on Radiation Protection (NCRP) Report No. 116, Limitation of Exposure to Ionizing Radiation, outlines the goals and philosophies of radiation protection in Chapter 2 of that document. The specific objectives are: 1. “To prevent the…
9.1 Introduction First proposed by Robert Wilson in 1946, radiation therapy with proton beams quickly became a reality with the first patient treatments performed in 1954 at Lawrence Berkeley National Labs. Starting in 1961 the Harvard Cyclotron Lab began treating…
8.1 Introduction Brachytherapy is defined as the temporary or permanent application of small, sealed radioactive sources in close proximity to or within the target volume. The treatment dose distribution is characterized by localized high dose and a steep dose drop-off.…
7.1 Introduction A key component of safe and effective modern radiotherapy is the ability to align a patient with respect to the radiation beam during treatment. Current means of accomplishing this include 3D visualization of soft tissue structures (via computed…