Introduction This year in the United States, an estimated 45,220 people will be diagnosed with pancreatic cancer and 38,460 will die from the disease . Although pancreatic cancer is the 10th most commonly diagnosed cancer in the United States, it…
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Acknowledgments TTW and EMC were supported by NSF grants CCF-0926194 and 0926181. HG was supported by the new faculty start-up grant from the Saint Louis University. Introduction Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer, arising…
Acknowledgements This work was partially supported by the Spanish National Bioinformatics Institute (INB) and grants BIO2012-40205, SAF2011-29530 (MINECO, Spain) and COST Action #BM1204: EU_Pancreas (European Cooperation in Science and Technology). Introduction The technology revolution by the Human Genome Project from…
Introduction Pancreatic cancer (PC) is a highly aggressive malignancy and ranks as the fourth leading cause of cancer-related death in the United States . This high mortality is partly due to the absence of specific symptoms and signs, and the…
Introduction Pancreatic ductal adenocarcinoma (PDAC) comprises the fourth most common cause of cancer lethality in Western countries with a less than 5% reported five-year survival . General increases in the life expectancy of citizens in industrialized countries primarily lead to…
Acknowledgments I would like to thank the following colleagues: Prof. Ugo Boggi, General and Transplants Surgery, University of Pisa, Italy; Prof. Daniela Campani, Surgical Pathology, University of Pisa, Italy; Prof. Marco Del Chiaro, General Surgery, CLINTEC Karolinska, Sweden; Prof. Irene…
Introduction Pancreatic cancer is a relatively rare cancer type, but a major cause of cancer-related death because there are quite rare histologically proven long-time survivors of pancreatic cancer. The main reasons for the worse prognosis are: late clinical presentation, aggressive…