Cardio-Oncology Practice Manual: A Companion to Braunwald’s Heart Disease

Bone marrow transplantation risks

Open full size image KEY POINTS Hematopoietic stem cell transplantation (HSCT) involves the infusion of multipotent hematopoietic stem cells, usually derived from the bone marrow, peripheral blood, or umbilical cord, and using cells from either the patient him-/herself (autologous), a…

Radiation therapy cardiovascular risks

Open full size image KEY POINTS Radiation therapy can lead to various forms of cardiovascular disease, including cardiomyopathy, heart failure, coronary artery disease, valvular heart disease, pericardial disease, and autonomic dysfunction. Dose sparing is the single most important preventive strategy,…

Cardiovascular risks of chemotherapy

Open full size image KEY POINTS Cancer therapies can be associated with a broad range of cardiovascular toxicities The three most important cardiovascular toxicities in terms of reported incidence and severity are 1) cardiomyopathy and heart failure, 2) vascular toxicities…