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Dilated cardiomyopathy (DCM) encompasses a wide range of conditions in which the primary disorder is the enlargement of the ventricular chambers with normal left ventricular (LV) wall thickness, which ultimately leads to reduced LV contractile function and symptoms of heart…
As the burden of heart failure (HF) and cardiomyopathies continues to rise, the clinical need for early detection of individuals at risk becomes critical. Identification of patients with a poor prognosis allows for early interventions (primary prevention, medications, devices) that…
Dilated cardiomyopathy (DCM) is an important cause of heart failure worldwide. The annual global prevalence of DCM is estimated at 40 cases per 100,000 persons, and the annual incidence is estimated at 7 cases per 100,000 persons. Approximately 10,000 deaths…
Myocarditis is a pathophysiological condition defined as infiltration of the myocardium by inflammatory cells with associated degenerative and necrotic changes not typical of ischemic injury. In severe cases, myocarditis is characterized by a rapid onset of heart failure symptoms. Although…
In clinical practice, regular exercise is encouraged as an essential strategy in the prevention of incident coronary artery disease and heart failure. Regular, intense, and rigorous bouts of exercise, largely at a competitive level, have been associated with alterations in…
Hypertrophic cardiomyopathy (HCM) is a primary disease of cardiac muscle characterized by a hypertrophied, nondilated left ventricle unassociated with other cardiac diseases that can reasonably account for the magnitude of hypertrophy present. The distribution of left ventricular hypertrophy (LVH), the…
Acknowledgment The authors would acknowledge Dr. Maithri Siriwardena, who was a coauthor of this chapter in the second edition of the textbook. Hypertrophic cardiomyopathy (HCM) is a common genetic cardiac disorder. The prevalence of overt HCM (using the threshold of…
Acknowledgment The authors acknowledge Dr. Paul Szmitko, who was the first author of this chapter in the second edition of the textbook. Dynamic left ventricular outflow tract obstruction (LVOTO) is an important clinical feature of hypertrophic cardiomyopathy (HCM). Resting or…
Acknowledgment The authors thank Dr. Christiane Gruner for her contribution to the previous edition of this chapter. Left ventricular (LV) hypertrophy (LVH) can represent either a physiologic or pathologic cardiac process that can be secondary to abnormal loading conditions or…